Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (2024)

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Prescription Required

Marketer

Knoll Pharmaceuticals Ltd

SALT COMPOSITION

Metformin (500mg)

Storage

Store below 30°C

Product introduction

Metform 500mg Tablet is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Metform 500mg Tablet is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of this medicine include diarrhea, nausea, vomiting, flatulence, weakness, indigestion, abdominal discomfort, headache, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.

Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Metform Tablet

Side effects of Metform Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metform

  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Headache
  • Abdominal discomfort
  • Weakness
  • Flatulence
  • Loss of appetite

How to use Metform Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metform 500mg Tablet is to be taken with food.

How Metform Tablet works

Metform 500mg Tablet is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Metform 500mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Metform 500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

Metform 500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Metform 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metform 500mg Tablet may be needed. Please consult your doctor.
Use of Metform 500mg Tablet is, however, not recommended in patients with severe kidney disease.

Liver

UNSAFE

Metform 500mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Metform Tablet?

If you miss a dose of Metform 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Metform 500mg Tablet

₹1.77/Tablet

Almetfor 500mg Tablet

Alkem Laboratories Ltd

₹1.18/tablet

33% cheaper

Biciphage 500 Tablet

Biochem Pharmaceutical Industries

₹1.2/tablet

32% cheaper

Metrose 500mg Tablet

Zeelab Pharmacy Pvt Ltd

₹0.63/tablet

64% cheaper

Elcephase 500mg Tablet

Elder Pharmaceuticals Ltd

₹1.29/tablet

27% cheaper

View all substitutes

Quick tips

  • You have been prescribed Metform 500mg Tablet to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metform 500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Prolonged use of Metform 500mg Tablet may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
  • Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.

Fact Box

Chemical Class

Biguanides Derivative

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Interaction with drugs

Taking Metform with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Ketotifen

Brand(s)

:

Ketotag, Ketotide, Airyfen

Life-threatening

Amiloride

Brand(s)

:

Amiur

Serious

Beclometasone

Brand(s)

:

Becoride, Rhinase, Bevent

Serious

Betamethasone

Brand(s)

:

Densol

Serious

View all interactions

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Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (2)

User feedback

What are you using Metform Tablet for?

Type 2 diabet*

100%

*

Type 2 diabetes mellitus

How much was the improvement?

Excellent

100%

What were the side-effects while using Metform 500mg Tablet?

No Side Effec*

100%

*

No Side Effect

FAQs

Q. What does Metform 500mg Tablet do exactly?

People with type 2 diabetes are not able to respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metform 500mg Tablet acts in several ways to reduce the increased levels of sugar in blood. Metform 500mg Tablet decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Q. Does Metform 500mg Tablet cause weight loss?

Yes, Metform 500mg Tablet has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Q. What are the benefits of taking Metform 500mg Tablet?

Metform 500mg Tablet is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metform 500mg Tablet when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Q. Can Metform 500mg Tablet make you sleepy?

Metform 500mg Tablet usually does not cause sleepiness and is well tolerated. However, the use of Metform 500mg Tablet may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metform 500mg Tablet.

Q. How to take Metform 500mg Tablet?

Take Metform 500mg Tablet with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metform 500mg Tablet with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

Q. What does Metform 500mg Tablet do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metform 500mg Tablet acts in several ways to reduce the increased levels of sugar in blood. Metform 500mg Tablet decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Q. Does Metform 500mg Tablet cause weight loss?

Yes, Metform 500mg Tablet has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Q. What are the benefits of taking Metform 500mg Tablet?

Metform 500mg Tablet is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metform 500mg Tablet when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Q. Can Metform 500mg Tablet make you sleepy?

Metform 500mg Tablet usually does not cause sleepiness and is well tolerated. However, the use of Metform 500mg Tablet may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metform 500mg Tablet.

Q. How to take Metform 500mg Tablet?

Take Metform 500mg Tablet with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metform 500mg Tablet with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.

  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.

  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.

  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (3)

  5. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (4)

  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (5)

  7. Metformin [EMC Label]. Middlesex, UK: Merck Serono Ltd.; 2020. [Accessed 27 Sep. 2021]. (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (6)

  8. Metformin [FDA Label]. Princeton, NJ: Bristol-Myers Squibb Company; 2017. [Accessed 26 Sept. 2021] (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (7)

  9. Metformin [FDA Label]. Hyderabad: Granules India Limited; 2016. [Accessed 27 Sept. 2021]. (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (8)

  10. Metformin Hydrochloride [Package Insert]. Verna, Goa: Sanofi India Limited; 2021. [Accessed 11 Jul. 2023]. (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (9)

  11. National Health Service. Pregnancy, breastfeeding and fertility while taking metformin. [Last Reviewed: 24 Mar. 2022]. [Accessed 11 Jul. 2023]. (online) Available from:Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (10)

Marketer details

Name: Knoll Pharmaceuticals Ltd

Address: M-17, Pharma Tower, Basem*nt & Ground Floor, Badli Industrial Area, New Delhi 110 042

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

Lab tests offered by us

Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (11)

Related/Popular tests

  • CBC (Complete Blood Count)
  • FBS (Fasting Blood Sugar)
  • HbA1c (Hemoglobin A1c)
  • PPBS (Postprandial Blood Sugar)
  • Lipid Profile
  • Vitamin D (25-Hydroxy)
  • Coronavirus Covid-19 Test- RT-PCR
  • LFT (Liver Function Test)
  • KFT (Kidney Function Test)
  • TSH (Thyroid Stimulating Hormone) Ultrasensitive
  • ESR (Erythrocyte Sedimentation Rate)
  • Uric Acid
  • Vitamin B12
  • CRP (C-Reactive Protein) - Quantitative
  • Urine C/S (Urine Culture and Sensitivity)
  • Serum Electrolytes
  • Serum Calcium
  • Serum Creatinine
  • KFT with Electrolytes (Kidney Function Test with Electrolytes)
  • Cholesterol - Total
  • Hb (Hemoglobin)
Metform 500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (2024)
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